Against All Odds
Natalia Rios is a lovely young girl who lives with her aunt Inez in the beautiful town of Comala, in the Mexican state of Colima. Her aunt’s husband, Arcadio, is a shameless character who tries to rape Natalia and ends up selling her into white slavery to a gang of hoodlums. One of them, Valente, takes pity on the innocent young girl. He saves her and they both run away, but are soon found by the criminals. Valente confronts them to give Natalia a chance to escape and is badly wounded. Natalia is able to get away and goes back to her aunt, only to find her on her deathbed. Inez tells her that, from now on, she must live with Doña Carlota at the home of the wealthy Serrano family. When Natalia arrives at the mansion, Don Teodoro Serrano and his daughter Sandra welcome her with open arms, but his wife Apolonia, Doña Carlota’s daughter, treats her with contempt.
Sebastian lives in the nearby town of Santa Cruz del Mar with his adoptive family: Amparo, who has always rejected him; her son Eduardo, who loves and is loyal to Sebastian, thinking they are really brothers; and the grandmother, Doña Cruz. One night, Eduardo is attacked by a drunkard and Sebastian defends him, leaving the attacker unconscious in the street. A street bum who witnessed the fight then robs and kills the man, but Sebastian is blamed for the murder and sent to prison.
Years later, Natalia and Eduardo become friends in collage. She is truly fond of him, but only as a friend. Eduardo, however, falls madly in love with her. Sebastian is released for good behavior and meets Natalia during an embarrassing incident where he must defend her from his inebriated friends. Even though they haven’t met again after that first encounter, Natalia and Sebastian cannot stop thinking about each other, and Eduardo and Sebastian do not realize that they have fallen in love with the same woman.
Sebastian is desperate because no one will give him a job, so he decides to try his luck in Mexico City. There, fate brings him face to face with Natalia once more, and they finally confess their love for each other. Natalia promises to find him work at the Serrano family’s tuna cannery, where she herself is employed, and they both go back to Comala. Meanwhile, Apolonia is searching for the illegitimate son she had in her youth and gave in adoption to Amparo’s husband. Amparo sees the chance to benefit her own child and tells Apolonia that Eduardo is her son. In an attempt to win his love, Apolonia gives him a job at the cannery and decides to make all his wishes come true. When she learns that Eduardo is in love with Natalia, Apolonia does everything in her power to force her to marry him, but Natalia’s love belongs to Sebastian and she will not give in to Apolonia’s pressure.
It is only when Eduardo falls gravelly ill and is not expected to live long that Natalia must decide whether she should marry him out of compassion, or be true to her heart and defend her love for Sebastian "Against All Odds".